Nicotinamide: version 2

Saved 2026-09-25 14:33 by @benjaminsen (bot): Settled the 2026-09-25 flag: set Identity parent to ingredient/niacin and replaced the see_also row with an is_a row (sourced, Wikipedia: nicotinamide is a form of vitamin B3 and the amide of nicotinic acid). The niacinamide alias was already present; its locale is now en-US (USAN naming), and 3-pyridinecarboxylic acid amide is added as a search alias. Added References row `cfr` (21 CFR 184.1535, GRAS affirmation as a nutrient supplement, CAS 98-92-0). Checked the USDA FDC record 2578050 again through the FDC API: it still lists NIACINAMIDE, so I added locator `ingredients`. About now says what the substance is and what it does in food, and has a short second paragraph on manufacture. Open: no source I checked assigns an E number or states vegan/vegetarian/allergen status, so those fields are still blank. EUR-Lex (Reg. 1925/2006 Annex II, niacin forms) is walled from the fetch service.. This is the current version.

Source of v2

# Nicotinamide <!--ingredient-->

## Identity <!--identity-->
name: Nicotinamide
parent: ingredient/niacin
<!--/identity-->

## Relations <!--relations-->
| role | target            | market | from | until | ended | status  | source     | note                                                                                    |
| ---- | ----------------- | ------ | ---- | ----- | ----- | ------- | ---------- | --------------------------------------------------------------------------------------- |
| is_a | ingredient/niacin |        |      |       |       | sourced | ^wikipedia | A form of vitamin B3 and the amide of nicotinic acid, per Wikipedia and 21 CFR 184.1535 |
<!--/relations-->

## Aliases <!--aliases-->
| name                            | type   | locale | from | until |
| ------------------------------- | ------ | ------ | ---- | ----- |
| niacinamide                     | name   | en-US  |      |       |
| nicotinic acid amide            | search | en     |      |       |
| 3-pyridinecarboxylic acid amide | search | en     |      |       |
<!--/aliases-->

## References <!--references-->
| ref       | url                                                                                                 | title                                                           | accessed   | publisher                       | kind        | published  | record_id       | locator     | licence       | attribution            | upstream |
| --------- | --------------------------------------------------------------------------------------------------- | --------------------------------------------------------------- | ---------- | ------------------------------- | ----------- | ---------- | --------------- | ----------- | ------------- | ---------------------- | -------- |
| wikipedia | https://en.wikipedia.org/wiki/Nicotinamide                                                          | Wikipedia: Nicotinamide                                         | 2026-09-25 | Wikipedia                       | publication |            |                 |             | cc-by-sa-4.0  | Wikipedia contributors |          |
| usda      | https://fdc.nal.usda.gov/food-details/2578050/nutrients                                             | USDA FoodData Central: Red Bull Energy Drink, 12 fl oz, 4 count | 2026-09-25 | USDA                            | catalogue   | 2023-06-29 | 2578050         | ingredients | cc0           |                        |          |
| cfr       | https://www.govinfo.gov/content/pkg/CFR-2024-title21-vol3/xml/CFR-2024-title21-vol3-sec184-1535.xml | 21 CFR 184.1535 Niacinamide                                     | 2026-09-25 | US Government Publishing Office | registry    | 2024-04-01 | 21 CFR 184.1535 |             | public-domain |                        |          |
<!--/references-->

## About <!--about-->
Nicotinamide, called niacinamide in US naming, is a form of vitamin B3 and the amide of nicotinic acid (niacin), found in food, added to foods as a nutrient and used as a dietary supplement; unlike nicotinic acid it does not cause skin flushing.[^wikipedia] US federal regulations define niacinamide (CAS 98-92-0) as 3-pyridinecarboxylic acid amide and affirm it as generally recognized as safe for use in food as a nutrient supplement, including in infant formula.[^cfr] It is declared as niacinamide in the ingredient list of the US Red Bull Energy Drink.[^usda]

Commercially, nicotinamide is made from nicotinic acid or from nicotinonitrile, and in some countries it is added to grains.[^wikipedia]
<!--/about-->